Is Metolazone Potassium Sparing No matter how talented you are, you can t be omniscient. Potassium-sparing diuretics (amiloride, triamterene, spironolactone, and eplerenone) are active in the distal tubule and inhibit the exchange of sodium for potassium. Metolazone is a very powerful agent and together with loop diuretics can cause a substantial loss of electrolytes and fluid. Metolazone has the molecular formula C 16 H 16 ClN 3 O 3 S, the chemical name 7-chloro-1, 2, 3, 4-tetrahydro-2-methyl-3- (2-methylphenyl)-4-oxo-6-quinazolinesulfonamide, and a molecular weight of 365.83. The most potent diuretics are the loop diuretics, followed by mannitol, metolazone (a thiazide-like diuretic), the thiazides, and the potassium-sparing diuretics The potency of diuretics is a function of where they work in the nephron to inhibit sodium and water resorption. Is Metolazone a potassium sparing diuretic? - FindAnyAnswer.com addition of a potassium sparing diuretic instituted if indicated. The increased delivery of sodium to the distal tubular exchange site results in increased potassium excretion. Example(s): Clorpres,Tenoretic,Thalitone (chlorthalidone and chlorthalidone combinations),Capozide,Dyazide,Hyzaar,Lopressor HCT,Maxzide,Prinzide (hydrochlorothiazide and hydrochlorothiazide combinations) (bumetanide),Lasix (furosemide),Demadex (torsemide) (amiloride and amiloride combinations),Aldactazide,Aldactone (spironolactone and spironolactone combinations),Dyazide,Maxzide (triamterene . (See . Get Cheap Lasix in our Pharmacy! Renal Agents Flashcards | Chegg.com Herein, is Metolazone potassium sparing? Thiazide and thiazide-like diuretics adverse effects: . (See . The actions of Metolazone result from interference with the renal tubular mechanism of electrolyte reabsorption. Metaxalone, a muscle relaxant, is a medicine with a similar name.. Metolazone is a thiazide diuretic marketed under the brand names Zaroxolyn and Mykrox.It is primarily used to treat congestive heart failure and high blood pressure. Chlorthlidone (Hygroton) -Thiazide-like diuretic/long acting -Most potent long acting. Thiazide diuretics alone or in combination with a potassium-sparing diuretic on blood pressure-lowering in patients with primary hypertension: protocol for a systematic review and network meta-analysis .
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